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Registros recuperados : 10 | |
3. | | JARDIM, A. M. da R. F.; SILVA, T. G. F. da; SOUZA, L. S. B. de; ARAÚJO JÚNIOR, G. do N.; ALVES, H. K. M. N.; SOUZA, M. de S.; ARAUJO, G. G. L. de; MOURA, M. S. B. de. Intercropping forage cactus and sorghum in a semi-arid environment improves biological efficiency and competitive ability through interspecific complementarity. Journal of Arid Environments, v. 188, 2021. Biblioteca(s): Embrapa Semiárido. |
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4. | | OLIVEIRA, P. S. N. de; COUTINHO, L. L.; CESAR, A. S. M.; DINIZ, W. J. da S.; SOUZA, M. de S.; ANDRADE, B. G.; KOLTES, J. E.; MOURÃO, G. B.; ZERLOTINI NETO, A.; REECY, J. M.; REGITANO, L. C. de A. Co-expression networks reveal potential regulatory roles of miRNAs in fatty acid composition of nelore cattle. Frontiers in Genetics, v. 10, p. 1-14, July 2019. Article 651. Na publicação: Adhemar Zerlotini, Luciana C.A. Regitano. Biblioteca(s): Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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5. | | SILVA, G. I. N.; JARDIM, A. M. da R. F.; SOUZA, M. de S.; ARAÚJO JÚNIOR, G. do N.; MORAIS, J. E. F. de; SOUZA, L. S. B. de; SOUZA, C. A. A. de; ALVES, C. P.; ARAUJO, G. G. L. de; MONTENEGRO, A. A. de A.; LIMA, B. L. de C.; SILVA, T. G. F. da. Combined agricultural practices in millet and cactus: phyllochron, structural characteristics and relations with yield. Scientia Agrícola, v. 80, e20220046, 2023. Biblioteca(s): Embrapa Semiárido. |
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6. | | SOUZA, M. de S.; SILVA, T. G. F. da; SOUZA, L. S. B. de; ALVES, H. K. M. N.; LEITE, R, M. C.; SOUZA, C. A. A. de; ARAUJO, G. G. L. de; CAMPOS, F. S.; SILVA, M. J. da; SOUZA, P. J. de O. P. de. Growth, phenology and harvesting time of cactus-millet intercropping system under biotic mulching. Archives of Agronomy and Soil Science, v. 68, n. 6. 764-778, 2020. Biblioteca(s): Embrapa Semiárido. |
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7. | | JARDIM, A. M. da R. F; SANTOS, H. R. B.; ALVES, H. K. M. N.; SILVA, S. L. F.; SOUZA, L. S. B. de; ARAÚJO JÚNIOR, G. do N.; SOUZA, M. de S.; ARAUJO, G. G. L. de; SOUZA, C. A. A. de; SILVA, T. G. F. da. Genotypic differences relative photochemical activity, inorganic and organic solutes and yield performance in clones of the forage cactus under semi-arid environment. Plant Physiology and Biochemistry, v. 162, p. 421-430, 2021. Biblioteca(s): Embrapa Semiárido. |
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8. | | AFONSO, J.; FORTES, M. R. S.; REVERTER, A.; DINIZ, W. J. da S.; CESAR, A. S. M.; LIMA, A. O. de; PETRINI, J.; SOUZA, M. de S.; COUTINHO, L. L.; MOURÃO, G. B.; ZERLOTINI NETO, A.; GROMBONI, C. F.; NOGUEIRA, A. R. A.; REGITANO, L. C. de A. Genetic regulators of mineral amount in Nelore cattle muscle predicted by a new co-expression and regulatory impact factor approach. Scientific Reports, v. 10, n. 1, p. 1-16, 2020 Article: 8436. Biblioteca(s): Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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9. | | LIMA, A. O. de; KOLTES, J. E.; DINIZ, W. J. S.; OLIVEIRA, P. S. N. de; CESAR, A. S. M.; TIZIOTO, P. L.; AFONSO, J.; SOUZA, M. de S.; PETRINI, J.; ROCHA, M. I. P.; CARDOSO, T. F.; ZERLOTINI NETO, A.; COUTINHO, L. L.; MOURÃO, G. B.; REGITANO, L. C. de A. Potential biomarkers for feed efficiency-related traits in nelore cattle identified by co-expression network and integrative genomics analyses. Frontiers in Genetics, v. 11, p. 1-14, Mar. 2020. Article 189. Na publicação: Luciana C. A. Regitano. Biblioteca(s): Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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10. | | ARAÚJO JÚNIOR, G. do N.; SILVA, T. G. F. da; SOUZA, L. S. B. de; SOUZA, M. de S.; ARAUJO, G. G. L. de; MOURA, M. S. B. de; SANTOS, J. P. A. de S.; JARDIM, A. M. da R. F.; ALVES, C. P.; ALVES, H. K. M. N. Productivity, bromatological composition and economic benefits of using irrigation in the forage cactus under regulated deficit irrigation in a semiarid environment. Bragantia, v. 80, jan. 2021. Biblioteca(s): Embrapa Semiárido. |
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Registros recuperados : 10 | |
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Registro Completo
Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
Data corrente: |
24/07/2019 |
Data da última atualização: |
09/01/2020 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
OLIVEIRA, P. S. N. de; COUTINHO, L. L.; CESAR, A. S. M.; DINIZ, W. J. da S.; SOUZA, M. de S.; ANDRADE, B. G.; KOLTES, J. E.; MOURÃO, G. B.; ZERLOTINI NETO, A.; REECY, J. M.; REGITANO, L. C. de A. |
Afiliação: |
PRISCILA S. N. DE OLIVEIRA, CPPSE; LUIZ L. COUTINHO, Esalq/USP; ALINE S. M. CESAR, Esalq/USP; WELLISON J. DA SILVA DINIZ, UFSCar; MARCELA M. DE SOUZA, Iowa State University; BRUNO G. ANDRADE, CPPSE; JAMES E. KOLTES, Iowa State University; GERSON B. MOURÃO, Esalq/USP; ADHEMAR ZERLOTINI NETO, CNPTIA; JAMES M. REECY, Iowa State University; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
Título: |
Co-expression networks reveal potential regulatory roles of miRNAs in fatty acid composition of nelore cattle. |
Ano de publicação: |
2019 |
Fonte/Imprenta: |
Frontiers in Genetics, v. 10, p. 1-14, July 2019. |
DOI: |
10.3389/fgene.2019.00651 |
Idioma: |
Inglês |
Notas: |
Article 651. Na publicação: Adhemar Zerlotini, Luciana C.A. Regitano. |
Conteúdo: |
Fatty acid (FA) content affects the sensorial and nutritional value of meat and plays a significant role in biological processes such as adipogenesis and immune response. It is well known that, in beef, the main FAs associated with these biological processes are oleic acid (C18:1 cis9, OA) and conjugated linoleic acid (CLA-c9t11), which may have beneficial effects on metabolic diseases such as type 2 diabetes and obesity. Here, we performed differential expression and co-expression analyses, weighted gene co-expression network analysis (WGCNA) and partial correlation with information theory (PCIT), to uncover the complex interactions between miRNAs and mRNAs expressed in skeletal muscle associated with FA content. miRNA and mRNA expression data were obtained from skeletal muscle of Nelore cattle that had extreme genomic breeding values for OA and CLA. Insulin and MAPK signaling pathways were identified by WGCNA as central pathways associated with both of these fatty acids. Co-expression network analysis identified bta-miR-33a/b, bta-miR-100, bta-miR-204, bta-miR-365-5p, btamiR-660, bta-miR-411a, bta-miR-136, bta-miR-30-5p, bta-miR-146b, bta-let-7a-5p, bta-let-7f, bta-let-7, bta-miR 339, bta-miR-10b, bta-miR 486, and the genes ACTA1 and ALDOA as potential regulators of fatty acid synthesis. This study provides evidence and insights into the molecular mechanisms and potential target genes involved in fatty acid content differences in Nelore beef cattle, revealing new candidate pathways of phenotype modulation that could positively benefit beef production and human consumption. MenosFatty acid (FA) content affects the sensorial and nutritional value of meat and plays a significant role in biological processes such as adipogenesis and immune response. It is well known that, in beef, the main FAs associated with these biological processes are oleic acid (C18:1 cis9, OA) and conjugated linoleic acid (CLA-c9t11), which may have beneficial effects on metabolic diseases such as type 2 diabetes and obesity. Here, we performed differential expression and co-expression analyses, weighted gene co-expression network analysis (WGCNA) and partial correlation with information theory (PCIT), to uncover the complex interactions between miRNAs and mRNAs expressed in skeletal muscle associated with FA content. miRNA and mRNA expression data were obtained from skeletal muscle of Nelore cattle that had extreme genomic breeding values for OA and CLA. Insulin and MAPK signaling pathways were identified by WGCNA as central pathways associated with both of these fatty acids. Co-expression network analysis identified bta-miR-33a/b, bta-miR-100, bta-miR-204, bta-miR-365-5p, btamiR-660, bta-miR-411a, bta-miR-136, bta-miR-30-5p, bta-miR-146b, bta-let-7a-5p, bta-let-7f, bta-let-7, bta-miR 339, bta-miR-10b, bta-miR 486, and the genes ACTA1 and ALDOA as potential regulators of fatty acid synthesis. This study provides evidence and insights into the molecular mechanisms and potential target genes involved in fatty acid content differences in Nelore beef cattle, revealing new candidate... Mostrar Tudo |
Palavras-Chave: |
Ácido linoleico conjugado; Ácido oleico; Ácidos graxos; Genômica; Integrative genomics; MiRNA; MRNA; Redes de co-expressão. |
Thesagro: |
Bos Indicus; Gado de Corte. |
Thesaurus NAL: |
Beef cattle; Conjugated linoleic acid; Oleic acid. |
Categoria do assunto: |
-- L Ciência Animal e Produtos de Origem Animal |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/199817/1/AP-Coexpression-networks.pdf
|
Marc: |
LEADER 02877naa a2200421 a 4500 001 2110872 005 2020-01-09 008 2019 bl uuuu u00u1 u #d 024 7 $a10.3389/fgene.2019.00651$2DOI 100 1 $aOLIVEIRA, P. S. N. de 245 $aCo-expression networks reveal potential regulatory roles of miRNAs in fatty acid composition of nelore cattle.$h[electronic resource] 260 $c2019 500 $aArticle 651. Na publicação: Adhemar Zerlotini, Luciana C.A. Regitano. 520 $aFatty acid (FA) content affects the sensorial and nutritional value of meat and plays a significant role in biological processes such as adipogenesis and immune response. It is well known that, in beef, the main FAs associated with these biological processes are oleic acid (C18:1 cis9, OA) and conjugated linoleic acid (CLA-c9t11), which may have beneficial effects on metabolic diseases such as type 2 diabetes and obesity. Here, we performed differential expression and co-expression analyses, weighted gene co-expression network analysis (WGCNA) and partial correlation with information theory (PCIT), to uncover the complex interactions between miRNAs and mRNAs expressed in skeletal muscle associated with FA content. miRNA and mRNA expression data were obtained from skeletal muscle of Nelore cattle that had extreme genomic breeding values for OA and CLA. Insulin and MAPK signaling pathways were identified by WGCNA as central pathways associated with both of these fatty acids. Co-expression network analysis identified bta-miR-33a/b, bta-miR-100, bta-miR-204, bta-miR-365-5p, btamiR-660, bta-miR-411a, bta-miR-136, bta-miR-30-5p, bta-miR-146b, bta-let-7a-5p, bta-let-7f, bta-let-7, bta-miR 339, bta-miR-10b, bta-miR 486, and the genes ACTA1 and ALDOA as potential regulators of fatty acid synthesis. This study provides evidence and insights into the molecular mechanisms and potential target genes involved in fatty acid content differences in Nelore beef cattle, revealing new candidate pathways of phenotype modulation that could positively benefit beef production and human consumption. 650 $aBeef cattle 650 $aConjugated linoleic acid 650 $aOleic acid 650 $aBos Indicus 650 $aGado de Corte 653 $aÁcido linoleico conjugado 653 $aÁcido oleico 653 $aÁcidos graxos 653 $aGenômica 653 $aIntegrative genomics 653 $aMiRNA 653 $aMRNA 653 $aRedes de co-expressão 700 1 $aCOUTINHO, L. L. 700 1 $aCESAR, A. S. M. 700 1 $aDINIZ, W. J. da S. 700 1 $aSOUZA, M. de S. 700 1 $aANDRADE, B. G. 700 1 $aKOLTES, J. E. 700 1 $aMOURÃO, G. B. 700 1 $aZERLOTINI NETO, A. 700 1 $aREECY, J. M. 700 1 $aREGITANO, L. C. de A. 773 $tFrontiers in Genetics$gv. 10, p. 1-14, July 2019.
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Embrapa Pecuária Sudeste (CPPSE) |
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